1 (03) 2016

Some questions on antihypertensive therapy of glaucoma

Veselovska Z.F.
Kyiv Medical University of UAFM, Kyiv, Ukraine
Kyiv City Eye Center, Kyiv City Clinical Hospital no. 1, Kyiv, Ukraine

Summary. The article presents the results of studies on the experience with glaucoma drugs of different pharmacological actions. It was determined that the achievement of low level of the intraocular pressure (IOP) is the necessary component of glaucoma therapy, and in patients with different stages of the disease it is important to reach the necessary level of relative decrease of IOP according to the stage of the primary open-angle glaucoma (POAG). This article includes the data of numerous works that demonstrate the privilege of glaucoma drugs on the base of travoprost, bimatoprost and latanoprost from group of prostaglandin analogues as first-line drugs for the correction of the IOP in patients with newly diagnosed POAG. There is the analysis of treatment strategy with the use of different groups of drugs in the complicated cases with high and bad corrected IOP. The expediency of inclusion in the treatment regime of fixed forms of glaucoma drugs is mainly based on combinations with prostaglandin analogues.

Thus, such approach in the shortest time allows reaching necessary hypo-effect for the stabilization of visual function. The appointment of adequate therapy in severe cases of POAG should be based on the fixed form of combined drugs. Very important is to keep strongly the policy of informing patients about possible side effects of eye drops, learning them with the rules instillation and maintaining the schedule of drops which are very important in lowering for the necessary level of IOP. The patients should be our partner during all process of the therapy of glaucoma.

Keywords: glaucoma, the compensation process, antihypertensive therapy, prostaglandin analogues, travoprost.

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