3Rigional Territorial Medical Association, Gorodishche, Ukraine
Summary. This article provides information about the efficacy, tolerability and safety of eye drops 0.0015 % tafluprost (Taflotan®, Santen, Finland) for the treatment of patients with glaucoma. Control of intraocular pressure (IOP) during the study was carried out at baseline and at 4–6 and 12 weeks after the start of application of eye drops Taflotan®. Also was еvаluаted the tolerability and safety of the drug. In primary open angle glaucoma after 12 weeks of monotherapy with tafluprost or combined treatment with tafluprost and beta-blockers showed a significant decrease in IOP. When pseudoexfoliative and pigmentary glaucoma, a significant reduction in IOP was recorded as in tafluprost monotherapy and combined treatment. In objective assessment of the impact of the drug on the surface of the eye Taflotan® shown that the prescription of tafluprost preservative-free not registered conjunctival hyperemia and the lack of negative influence in any of the surveyed patients.
It was found that the application of eye drops without preservative products Taflotan® tears and tear film stability remained normal throughout the period of treatment and observation. In the group of patients treated with Taflotan® preservative in the vial with a slight decrease tear secretion, tear film stability which were compensated with the additional purpose lubricants. Most patients rated tolerance of eye drops Taflotan® as «excellent» and «good».
Kharkiv National Medical University, Kharkiv, Ukraine
Summary. Glaucoma is one of the most important problems of ophthalmology. Primarily glaucoma affects the quality of life because it leads to the loss of the visual field. The reasons for late visit to an ophthalmologist, a relatively small number of cases of open-angle glaucoma detected in early stage, high level of disability – are the important issues of ophthalmology. Life quality assesments, the second important indicator, which allows you to obtain information about the value and importance of the constraints that result from the disease. Purpose is to get more strict representation about the visual field of the patient to the binocular visual sensitivity and to appreciate the degree of changes due to diseases of the patient with Esterman test and comparison with the data of the visual field examination.
The article presents the results of study of the changes occurring in the binocular field of vision in patients with primary open-angle glaucoma in comparison with changes in the monocular visual field and quality of life. The features of the influence of primary open-angle glaucoma in the quality of life of patients and the possible reasons for delays in seeking medical attention.
It is shown that open-angle glaucoma mostly affects the ability to perform tasks that require binocular field of view than the tasks for which the binocular field of view does not really matter. Therefore, in determining admission to the performance the work with special conditions (driving a car, work with machines, and so on) patients should be examined according to their condition of binocular visual field.
Aim. To еvаluаtе the safety, efficacy and possible additive role of flat fitting RGP lens following riboflavin-UVA corneal collagen cross-linking (CXL) in management of progressive keratoconus.
Subject and Method. Prospective comparative study of 30 eyes without RGP lens and 34 eyes fitted with RGP lens with apical bearing (flat fitting) from 2 to 10 weeks postCXL. None of the patients had been wearing contact lens (CL) before CXL. The effect of the CXL without and with RGP lens was measured by the change from the baseline of best spectacle corrected visual acuity (BSCVA), refractive sphere and cylinder, maximal keratometry value (Kmax), simulated keratometry, astigmatism and I-S value. The results of these measurements are reported pre-CXL and at 6-month intervals up to 24 months post-CXL.
Result. In the eyes without CL, none of the study parameters showed a significant change from baseline. Only in the group of eyes fitted with CL post-CXL, several parameters showed a significant improvement: refractive cylinder, I-S value, Kmax, simulated keratometry and astigmatism.
Conclusion. RGP lens with flat fitting can be a safe additive factor in improvement of topographical parameters following CXL.